Document Type
Patent
Publication Date
April 2014
Patent Number
8703963
CPC
C07D 263/26(20130101),
Abstract
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against Staphylococcus spp., including methicillin resistant Staphylcoccus aureus (MRSA), and Bacillus spp., including Bacillus anthracis.
Application Number
12/028,460
Recommended Citation
Turos, Edward; Mishra, Rajesh Kumar; Revell, Kevin; and Coates, Cristina M., "Derivative N-thiolated 2-oxazolidinone antibiotics" (2014). USF Patents. 104.
https://digitalcommons.usf.edu/usf_patents/104
Assignees
University of South Florida
Filing Date
02/08/2008
Primary/U.S. Class
548/230
