Presentation Type
Poster
Do Invasive Electrode Designs Predict Surgical Outcome in Patients With Intractable Epilepsy?
Abstract
BACKGROUND: In light of discordant diagnostic results during preoperative assessment, invasive EEGs are used to clarify: 1) whether a seizure patient is a viable candidate for resective surgery, 2) where the seizures originate (therefore, where to resect) and 3) how much to resect.
METHODS: We retrospectively collected data for 88 patients, focusing on those who underwent surgery and received a seizure outcome.
RESULTS: Of n=88 patients, 51/88 were female with a mean age of 31.9 years. 84/88 patients had at least one-year follow-up after surgery and 19/84 had no resective surgery. Of the remaining 65 patients, 36 had strips alone and 25 had both strips & grids implanted. 29/65 had multi-lobe implants while 46.2% (30/65) had implants solely in the temporal lobe. The most common electrode arrangements were bitemporal (29/65), unilateral multi-lobar (20/65), and unilateral multi-lobar (6/65). All n=65 patients received an Engel Classification (I=23/65, II=21/65, III=15/65, IV= 6/65). After statistics were applied, strips/grid designs were found to be unrelated to outcome (p-value >.05).
CONCLUSION: Electrode arrangement did not predict a favorable outcome (Class I). Other factors such as compliance with medical management and seizure characteristics must be considered if a predictor for optimal post-operative outcome is to be found.
Categories
Biomedical Sciences
Research Type
Course Related
Mentor Information
William O. Tatum IV, D.O.
Do Invasive Electrode Designs Predict Surgical Outcome in Patients With Intractable Epilepsy?
BACKGROUND: In light of discordant diagnostic results during preoperative assessment, invasive EEGs are used to clarify: 1) whether a seizure patient is a viable candidate for resective surgery, 2) where the seizures originate (therefore, where to resect) and 3) how much to resect.
METHODS: We retrospectively collected data for 88 patients, focusing on those who underwent surgery and received a seizure outcome.
RESULTS: Of n=88 patients, 51/88 were female with a mean age of 31.9 years. 84/88 patients had at least one-year follow-up after surgery and 19/84 had no resective surgery. Of the remaining 65 patients, 36 had strips alone and 25 had both strips & grids implanted. 29/65 had multi-lobe implants while 46.2% (30/65) had implants solely in the temporal lobe. The most common electrode arrangements were bitemporal (29/65), unilateral multi-lobar (20/65), and unilateral multi-lobar (6/65). All n=65 patients received an Engel Classification (I=23/65, II=21/65, III=15/65, IV= 6/65). After statistics were applied, strips/grid designs were found to be unrelated to outcome (p-value >.05).
CONCLUSION: Electrode arrangement did not predict a favorable outcome (Class I). Other factors such as compliance with medical management and seizure characteristics must be considered if a predictor for optimal post-operative outcome is to be found.
