Assessment of Cardiovascular Function and Microvascular Permeability in a Conscious Rat Model of Alcohol Intoxication Combined with Hemorrhagic Shock and Resuscitation
Document Type
Book Chapter
Publication Date
2018
Keywords
Hemorrhage, Shock, Alcohol, Microcirculation, Microvascular permeability, Electrocardiogram
Digital Object Identifier (DOI)
https://doi.org/10.1007/978-1-4939-7526-6_6
Abstract
Hypotension, cardiac depression, and elevated microvascular permeability are known problems that complicate resuscitation of patients following traumatic injury, particularly those who are also intoxicated from alcohol consumption. A conscious rat model of combined alcohol intoxication and hemorrhagic shock has been used to study the hemodynamic mechanisms involved. Here, we describe using this model to study microvascular leakage and cardiac electrical activity.
Was this content written or created while at USF?
Yes
Citation / Publisher Attribution
Assessment of Cardiovascular Function and Microvascular Permeability in a Conscious Rat Model of Alcohol Intoxication Combined with Hemorrhagic Shock and Resuscitation, in B. Tharakan (Eds.), Traumatic and Ischemic Injury, v. 1717, Humana Press, p. 61-81
Scholar Commons Citation
Doggett, Travis M.; Tur, Jared J.; Alves, Natascha; Yuan, Sarah Y.; Tipparaju, Srinicas M.; and Breslin, Jerome W., "Assessment of Cardiovascular Function and Microvascular Permeability in a Conscious Rat Model of Alcohol Intoxication Combined with Hemorrhagic Shock and Resuscitation" (2018). Pharmacy Faculty Publications. 70.
https://digitalcommons.usf.edu/pharm_facpub/70
