Title

Deterioration Following Improvement with TPA Therapy: Carotid Thrombosis and Reocclusion

Document Type

Article

Publication Date

2001

Abstract

Clinical improvement of ≥4 points on the NIH Stroke Scale (NIHSS) was seen in 47% of patients 24 hours after treatment with IV tissue plasminogen activator (tPA) for acute ischemic stroke.1 Arterial recanalization can be associated with early recovery;2 following improvement, however, 15% of patients experience clinical deterioration.3 Transcranial Doppler (TCD) ultrasonography has been used to detect arterial occlusion and monitor recanalization during thrombolysis.4 The authors report the clinical and TCD findings in a patient who improved, then subsequently deteriorated, while receiving tPA therapy.

Digital Object Identifier (DOI)

https://doi.org/10.1212/WNL.56.4.568

Citation / Publisher Attribution

Neurology, v. 56, issue 4, p. 568-570

Was this content written or created while at USF?

Yes

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