Deterioration Following Improvement with TPA Therapy: Carotid Thrombosis and Reocclusion
Document Type
Article
Publication Date
2001
Digital Object Identifier (DOI)
https://doi.org/10.1212/WNL.56.4.568
Abstract
Clinical improvement of ≥4 points on the NIH Stroke Scale (NIHSS) was seen in 47% of patients 24 hours after treatment with IV tissue plasminogen activator (tPA) for acute ischemic stroke.1 Arterial recanalization can be associated with early recovery;2 following improvement, however, 15% of patients experience clinical deterioration.3 Transcranial Doppler (TCD) ultrasonography has been used to detect arterial occlusion and monitor recanalization during thrombolysis.4 The authors report the clinical and TCD findings in a patient who improved, then subsequently deteriorated, while receiving tPA therapy.
Was this content written or created while at USF?
Yes
Citation / Publisher Attribution
Neurology, v. 56, issue 4, p. 568-570
Scholar Commons Citation
Burgin, W. Scott and Alexandrov, Andrei, "Deterioration Following Improvement with TPA Therapy: Carotid Thrombosis and Reocclusion" (2001). Neurology Faculty Publications. 29.
https://digitalcommons.usf.edu/neur_facpub/29
