Sex Disparities in Ischemic Stroke Care

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stroke, National Institute of Neurological Disorders and Stroke, sex characteristics, Get With The Guidelines


Background and Purpose—Sex-specific disparities in stroke care including thrombolytic therapy and early hospital admission are reported. In a large registry of Florida and Puerto Rico hospitals participating in the Get With The Guidelines—Stroke program, we sought to determine sex-specific differences in ischemic stroke performance metrics and overall thrombolytic treatment.

Methods—Around 51 317 (49% women) patients were included from 73 sites from 2010 to 2014. Multivariable logistic regression with generalized estimating equations evaluated sex-specific differences in the prespecified Get With The Guidelines—Stroke metrics for defect-free care in ischemic stroke, adjusting for age, race-ethnicity, insurance status, hospital characteristics, individual risk factors, and the presenting stroke severity.

Results—As compared with men, women were older (73±15 versus 69±14 years; P

Conclusions—Women received comparable stroke care to men in this registry as measured by prespecified Get With The Guidelines metrics. However, women less likely received thrombolysis and had door-to-needle time <1 >hour, an observation that calls for the implementation of interventions to reduce sex disparity in these measures.

Citation / Publisher Attribution

Stroke, v. 47, issue 10, p. 2618-2626