Sex Disparities in Ischemic Stroke Care

Authors

Negar Asdaghi, University of South Florida
Jose G. Romano, University of South Florida
Kefeng Wang, University of South Florida
Maria A. Ciliberti-Vargas, University of South Florida
Sebastian Koch, University of South Florida
Hannah Gardener, University of South Florida
Chuanhui Dong, University of South Florida
David Z. Rose, University of South FloridaFollow
Salina P. Waddy, University of South Florida
Mary Robichaux, University of South Florida
Enid J. Garcia, University of South Florida
Juan A. Gonzalez-Sanchez, University of South Florida
W. Scott Burgin, University of South FloridaFollow
Ralph L. Sacco, University of South Florida
Tatjana Rundek, University of South Florida

Document Type

Article

Publication Date

2016

Keywords

stroke, National Institute of Neurological Disorders and Stroke, sex characteristics, Get With The Guidelines

Abstract

Background and Purpose—Sex-specific disparities in stroke care including thrombolytic therapy and early hospital admission are reported. In a large registry of Florida and Puerto Rico hospitals participating in the Get With The Guidelines—Stroke program, we sought to determine sex-specific differences in ischemic stroke performance metrics and overall thrombolytic treatment.

Methods—Around 51 317 (49% women) patients were included from 73 sites from 2010 to 2014. Multivariable logistic regression with generalized estimating equations evaluated sex-specific differences in the prespecified Get With The Guidelines—Stroke metrics for defect-free care in ischemic stroke, adjusting for age, race-ethnicity, insurance status, hospital characteristics, individual risk factors, and the presenting stroke severity.

Results—As compared with men, women were older (73±15 versus 69±14 years; P

Conclusions—Women received comparable stroke care to men in this registry as measured by prespecified Get With The Guidelines metrics. However, women less likely received thrombolysis and had door-to-needle time <1 >hour, an observation that calls for the implementation of interventions to reduce sex disparity in these measures.

Citation / Publisher Attribution

Stroke, v. 47, issue 10, p. 2618-2626

Scholar Commons Citation

Asdaghi, Negar; Romano, Jose G.; Wang, Kefeng; Ciliberti-Vargas, Maria A.; Koch, Sebastian; Gardener, Hannah; Dong, Chuanhui; Rose, David Z.; Waddy, Salina P.; Robichaux, Mary; Garcia, Enid J.; Gonzalez-Sanchez, Juan A.; Burgin, W. Scott; Sacco, Ralph L.; and Rundek, Tatjana, "Sex Disparities in Ischemic Stroke Care" (2016). Neurology Faculty Publications. 17.
https://digitalcommons.usf.edu/neur_facpub/17