Title

Isolation and Characterization of a Novel Bat Coronavirus Closely Related to the Direct Progenitor of Severe Acute Respiratory Syndrome Coronavirus

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Publisher

American Society for Microbiology

Publication Date

February 2016

Abstract

We report the isolation and characterization of a novel bat coronavirus which is much closer to the severe acute respiratory syndrome coronavirus (SARS-CoV) in genomic sequence than others previously reported, particularly in its S gene. Cell entry and susceptibility studies indicated that this virus can use ACE2 as a receptor and infect animal and human cell lines. Our results provide further evidence of the bat origin of the SARS-CoV and highlight the likelihood of future bat coronavirus emergence in humans.

Notes

Journal of Virology, Vol. 90, no. 6 (2016-02-26).

Keywords

Isolation, Characterization, Novel Bat Coronavirus, Bat, Coronavirus, Sars

Description

RDA

Subject: topical

Isolation; Characterization; Novel Bat Coronavirus; Bat; Coronavirus; Sars

Type

Article

Genre

serial

Identifier

SFS0064409_00001

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