Isolation and Characterization of a Novel Bat Coronavirus Closely Related to the Direct Progenitor of Severe Acute Respiratory Syndrome Coronavirus
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Publication Date
February 2016
Abstract
We report the isolation and characterization of a novel bat coronavirus which is much closer to the severe acute respiratory syndrome coronavirus (SARS-CoV) in genomic sequence than others previously reported, particularly in its S gene. Cell entry and susceptibility studies indicated that this virus can use ACE2 as a receptor and infect animal and human cell lines. Our results provide further evidence of the bat origin of the SARS-CoV and highlight the likelihood of future bat coronavirus emergence in humans.
Keywords
Isolation, Characterization, Novel Bat Coronavirus, Bat, Coronavirus, Sars
Document Type
Article
Notes
Journal of Virology, Vol. 90, no. 6 (2016-02-26).
Identifier
SFS0064409_00001
Recommended Citation
Yang, Xing-Lou; Hu, Ben; and Wang, Bo, "Isolation and Characterization of a Novel Bat Coronavirus Closely Related to the Direct Progenitor of Severe Acute Respiratory Syndrome Coronavirus" (2016). KIP Articles. 2867.
https://digitalcommons.usf.edu/kip_articles/2867
