Inhibitor of Platelet Aggregation Present in Saliva of the Vampire Bat Desmodus rotundus

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Publication Date

November 1967

Abstract

A substance capable of inhibiting ADP‐induced and thrombin‐induced aggregation of human platelets in vitro has been found in saliva of D. rotundus. This substance does not act on ADP directly but probably exerts its effect on the platelet ADP‐binding sites or on the plasma co‐factor involved in this reaction. Partial separation of the aggregation inhibitor from other active substances in the saliva has been carried out using G‐200 Sephadcx.

Document Type

Article

Notes

The British Journal of Haematology, Vol. 13, no. 6 (1967-11).

Identifier

SFS0069823_00001

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