Document Type
Article
Publication Date
2014
Digital Object Identifier (DOI)
https://doi.org/10.1055/s-0034-1377175
Abstract
A woman (70-years) with a history of iron deficiency anemia and chronic kidney disease presented with two weeks of abdominal pain. Upper endoscopy demonstrated the gastric and duodenal mucosa was black and speckled consistent with diagnosis of pseudomelanosis. Biopsies showed pigment-laden macrophages in the lamina propria, which stained positive for iron and Masson-Fontana trichrome stain consistent with a “melanin-like” pigment. Although an uncommon endoscopic finding, this pigment has been associated with the use of certain medications, antihypertensives and iron supplements, and systemic illnesses, including hypertension, chronic kidney disease, gastric hemorrhage, and diabetes mellitus.
Rights Information
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Was this content written or created while at USF?
Yes
Citation / Publisher Attribution
Endoscopy International Open, v. 2, issue 3, p. E191-E192
Scholar Commons Citation
Caire, M. Thure; Kalan, Shivam; Brady, Patrick; and Gill, Jeffrey, "Pseudomelanosis of the Stomach and Duodenum: an Uncommon Endoscopic Finding" (2014). Internal Medicine Faculty Publications. 94.
https://digitalcommons.usf.edu/intmed_facpub/94