Disparities in cervical cancer characteristics and survival between white Hispanics and white non-Hispanic women

Authors

Hafiz Mohammad Rafiqullah Khan
Kemesha Gabbidon, University of South Florida St. PetersburgFollow
Anshul Saxena
Faheema Abdool-Ghany
John M. Dodge III
Taylor Lenzmeier

SelectedWorks Author Profiles:

Kemesha Gabbidon

Document Type

Article

Publication Date

2016

Abstract

Background:Cervical cancer is the second most common cancer among women resulting in nearly 500,000cases annually. Screening leads to better treatment and survival time. However, human papillomavirus (HPV)exposure, screening, and treatment vary among races and ethnicities in the United States. The purpose of thisstudy is to examine disparities in characteristics of cervical cancer and survival of cases between White Hispanic(WH) and White non-Hispanic (WNH) women in the United States.Methods:We used a stratified random sampling method to select cervical cancer patient records from ninestates; a simple random sampling method to extract the demographic and disease characteristics data withinstates from the Surveillance Epidemiology and End Results (SEER) database. We used statistical probabilitydistribution methods for discrete and continuous data. The chi-square test and independent samplest-testwere used to evaluate statistically significant differences. Furthermore, the Cox Proportional Regression andthe Kaplan–Meier survival estimators were used to compare WH and WNH population survival times in theUnited States.Results:The samples of WNH and WH women included 4,000 cervical cancer cases from 1973–2009. Therewere statistically significant differences between ethnicities: marital status (p<0.001); primary site of cancer(p<0.001); lymph node involvement (p<0.001); grading and differentiation (p<0.0001); and tumor behavior(p<0.001). The mean age of diagnosis for both groups showed no statistical differences. However, the meansurvival time for WNH was 221.7 (standard deviation [SD]=118.1) months and for WH was 190.3 (SD=120.3),which differed significantly (p<0.001).Conclusions:Clear disparities exist in risk factors, cervical cancer characteristics, and survival time betweenWH and WNH women.

Recommended Citation

Khan, Hafiz Mohammad Rafiqullah; Gabbidon, Kemesha; Saxena, Anshul; Abdool-Ghany, Faheema; Dodge, John M. III; and Lenzmeier, Taylor, "Disparities in cervical cancer characteristics and survival between white Hispanics and white non-Hispanic women" (2016). USF St. Petersburg campus Faculty Publications. 3764.
https://digitalcommons.usf.edu/fac_publications/3764

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