USF St. Petersburg campus Faculty Publications
Liver tests in dogs receiving anticonvulsant drugs (diphenylhydantoin and primidone).
Document Type
Article
Publication Date
1981
ISSN
0587-2871
Abstract
Two groups of adult female dogs were given diphenylhydantoin or primidone orally for 82 days. Plasma glutamic-pyruvic transaminase (GPT), alkaline phosphatase (AP) and gamma-glutamyl transferase (GGT) activity, total plasma bilirubin (TBR) concentration, fasting bile acid level and percent sulfobromophthalein (% BSP) retention were determined in the dogs prior to and after treatment. Plasma GPT and AP showed persistent increases in some dogs, while occasional increases occurred in the remaining dogs in both groups. The plasma enzymes returned to normal 5 wk after treatment. Plasma GGT, TBR, fasting bile acids and % BSP retention were normal during the study.
Language
en_US
Publisher
American Animal Hospital Association
Recommended Citation
Meyer, D.J., & Noonan, N.E. (1981). Liver tests in dogs receiving anticonvulsant drugs (diphenylhydantoin and primidone). Journal of the American Animal Hospital Association, 17(2), 261-264.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Comments
Abstract only. Full-text article is available only through licensed access provided by the publisher. Published in Journal of the American Animal Hospital Association, 17(2), 261-264.