Graduation Year

2020

Document Type

Thesis

Degree

M.S.P.H.

Degree Name

MS in Public Health (M.S.P.H.)

Degree Granting Department

Public Health

Major Professor

Russell Kirby, Ph.D., MS

Committee Member

Nicholas Carris, Pharm. D

Committee Member

Ronee Wilson, Ph.D.

Committee Member

Jean Paul Tanner, Ph.D., MPH

Keywords

Pregnancy, Singleton, Primigravida, Socio-demographic Disparities, Risk factors

Abstract

Gestational diabetes mellitus (GDM) and preeclampsia are serious complications of pregnancy which are associated with both short- and long-term adverse health outcomes for the mother as well as the fetus. The increase in prevalence of these conditions has become a major public health concern. The purpose of this study is to examine the association and risk imposed by GDM for preeclampsia in primigravid women. This descriptive study was conducted using data retrieved from the electronic medical records of a large integrated health system in Florida. The data for this analysis included pregnancy records for patients at least 18 years of age over a six-year period from 2011 – 2016. The study was limited to primigravida women with a singleton pregnancy. The risk of preeclampsia for GDM positive women was compared to non-GDM positive women. Chi-square tests and multivariable logistic regression models were performed to conduct the analysis. In this study, the prevalence of preeclampsia was slightly higher among GDM positive women around 9.1% compared to 7.4% in non-GDM positive women. Although the results did not reach statistical significance, the risk of preeclampsia was higher among women with GDM compared to women without GDM (AOR=1.33; 95% CI 0.9,2.1; p =0.1826). Therefore, it is necessary to develop programs and interventions with preventive efforts to reduce the rates of GDM and preeclampsia at patient and provider level.

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