Graduation Year
2023
Document Type
Dissertation
Degree
Ph.D.
Degree Name
Doctor of Philosophy (Ph.D.)
Degree Granting Department
Nursing
Major Professor
Constance Visovsky, Ph.D., RN, ACNP, FAAN
Committee Member
Theresa Beckie, Ph.D., MN, RN, FAHA, FAAN
Committee Member
Victoria Marshall, Ph.D., RN
Committee Member
Ming Ji, Ph.D.
Committee Member
Kristine Donovan, Ph.D.
Keywords
Anxiety, Cancer Survivor, Depression, Pain, Resilient, Well-Being
Abstract
The purpose of this dissertation study was to longitudinally examine psychological distress (depressive symptoms and anxiety symptoms), resilience, and the impact on quality of life (QOL) in breast cancer survivors (BCS) with taxane-induced peripheral neuropathy (TIPN). The specific aims were 1) to describe psychological distress (depressive and anxiety symptoms) in BCS with TIPN and the impact on QOL using a scoping review; 2) to determine the relationship between psychological distress, QOL, and resilience in BCS with TIPN over time in a 16-week randomized controlled trial (RCT); and 3) to determine if resilience moderates psychological distress and QOL in BCS with TIPN. The first aim used a scoping review to identify sources that examined psychological distress (depressive and anxiety symptoms) and QOL in BCS with TIPN. The scoping review identified eight studies that assessed psychological distress symptoms in BCS with TIPN and the impact that these symptoms had on QOL. The second aim used descriptive statistics, Pearson correlations, and linear mixed effects modeling to assess the relationships between these variables. From the longitudinal results from this study, it is clear that there is a need for a greater focus on psychological symptoms in BCS with TIPN. The third aim used descriptive statistics, Pearson correlations, mixed effects modeling, and moderation analysis. Results indicated that resilience was not a moderator for depressive symptoms and QOL in BCS with TIPN. However, this study still highlights the importance of resilience for BCS with TIPN and emphasizes the impact that depressive symptoms can have on QOL.
Scholar Commons Citation
Schwab, Lauren, "Psychological Distress, Resilience, and the Impact on Quality of Life in Breast Cancer Survivors With Taxane-Induced Peripheral Neuropathy" (2023). USF Tampa Graduate Theses and Dissertations.
https://digitalcommons.usf.edu/etd/10090
