Bacterial Cell Division: Nonmodels Poised to Take the Spotlight

Document Type

Article

Publication Date

2017

Keywords

Min system, FtsZ, DivIVA, nucleoid occlusion, Noc

Digital Object Identifier (DOI)

https://doi.org/10.1146/annurev-micro-102215-095657

Abstract

The last three decades have witnessed an explosion of discoveries about the mechanistic details of binary fission in model bacteria such as Escherichia coli, Bacillus subtilis, and Caulobacter crescentus. This was made possible not only by advances in microscopy that helped answer questions about cell biology but also by clever genetic manipulations that directly and easily tested specific hypotheses. More recently, research using understudied organisms, or nonmodel systems, has revealed several alternate mechanistic strategies that bacteria use to divide and propagate. In this review, we highlight new findings and compare these strategies to cell division mechanisms elucidated in model organisms.

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Citation / Publisher Attribution

Annual Review of Microbiology, v. 71, p. 393-411

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