Efficient synthesis of alkyl carbonates

Authors

Kyung Woon Jung

Document Type

Patent

Publication Date

October 2002

Patent Number

6469193

Abstract

Efficient synthetic methods towards mixed aliphatic carbonates through the three component couplings of aliphatic alcohols, alkyl halides and carbon dioxide in the presence of cesium carbonate and tetrabutylammonium iode (TBAI). Due to their enhanced nucleophilicities, cesium alkoxides are smoothly incorporated into CO₂, allowing for mild reaction conditions such as ambient temperatures and short reaction durations. Various primary and secondary substrates are compatible under the standard conditions, offering high yields, while chiral templates such as α-hydroxy carbonyls are resistant to racemization.

Application Number

09/513,218

Recommended Citation

Jung, Kyung Woon, "Efficient synthesis of alkyl carbonates" (2002). USF Patents. 795.
https://digitalcommons.usf.edu/usf_patents/795

Assignees

University of South Florida

Filing Date

02/25/2000

Primary/U.S. Class

558/275