Described are non-toxigenic Clostridium difficile strains and spores. Also described are vaccines comprising the Clostridium difficile spores. Further described are methods of preventing or treating a Clostridium difficile infection in a subject in need thereof.
Sun, Xingmin and Sonenshein, Abraham, "Non-toxigenic Clostridium difficile spores for use in oral vaccination" (2022). USF Patents. 1302.
University of South Florida