G01N 21/05, G01N 15/1484, G01N 21/0303, G01N 2201/0873, G01N 2021/0346, G01N 2021/058, G01N 21/7746, G01N 21/552, B01L 3/502761, B01L 2400/086, B01L 2300/0816, B01L 2200/0668, B01L 2300/0867
In one embodiment, a microfluidic platform for optical biosensing, the platform including an optical substrate, a layer provided on the substrate, and a channel formed within the layer and defined by the layer and the substrate through which fluid can flow, the channel including a channel constriction that gradually narrows along a length of the channel to a point at which the channel is physically sized and configured to trap a microsphere suspended in the fluid when the fluid flows through the channel so that the microsphere cannot pass the channel constriction.
Lutti, Julie and Wang, Jing, "Microfluidic platforms for optical biosensing" (2018). USF Patents. 1100.
University of South Florida