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Title

On the Potential Tole of Exosomes in the COVID-19 Reinfection/reactivation Opportunity

Document Type

Article

Publication Date

7-2020

Keywords

SARS-CoV-2, COVID-19, reinfection, exosome, extracellular vesicle

DOI

https://doi.org/10.1080/07391102.2020.1790426

Abstract

We propose here that one of the potential mechanisms for the relapse of the COVID-19 infection could be a cellular transport pathway associated with the release of the SARS-CoV-2-loaded exosomes and other extracellular vesicles. It is possible that this "Trojan horse" strategy represents possible explanation for the re-appearance of the viral RNA in the recovered COVID-19 patients 7-14 day post discharge, suggesting that viral material was hidden within such exosomes or extracellular vesicles during this "silence" time period and then started to re-spread again. Communicated by Ramaswamy H. Sarma.

Comments

Article available for free at PubMed Central: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441802/

Citation / Publisher Attribution

Journal of Biomolecular Structure & Dynamics, in press

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