Viral Diversity and Dynamics in an Infant Gut
Infant, Feces, Virus, Phage, Metagenomics, Microarray, Gut
Digital Object Identifier (DOI)
Metagenomic sequencing of DNA viruses from the feces of a healthy week-old infant revealed a viral community with extremely low diversity. The identifiable sequences were dominated by phages, which likely influence the diversity and abundance of co-occurring microbes. The most abundant fecal viral sequences did not originate from breast milk or formula, suggesting a non-dietary initial source of viruses. Certain sequences were stable in the infant's gut over the first 3 months of life, but microarray experiments demonstrated that the overall viral community composition changed dramatically between 1 and 2 weeks of age.
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Citation / Publisher Attribution
Research in Microbiology, v. 159, issue 5, p. 367-373
Scholar Commons Citation
Breitbart, Mya; Haynes, Matthew; Kelley, Scott; Angly, Florent; Edwards, Robert; Felts, Ben; Mahaffy, Joseph; Mueller, Jennifer; Nulton, James; Rayhawk, Steve; Rodriguez-Brito, Beltran; Salamon, Peter; and Rohwer, Forest, "Viral Diversity and Dynamics in an Infant Gut" (2008). Marine Science Faculty Publications. 770.