Marine Science Faculty Publications

Viral Diversity and Dynamics in an Infant Gut

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Infant, Feces, Virus, Phage, Metagenomics, Microarray, Gut

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Metagenomic sequencing of DNA viruses from the feces of a healthy week-old infant revealed a viral community with extremely low diversity. The identifiable sequences were dominated by phages, which likely influence the diversity and abundance of co-occurring microbes. The most abundant fecal viral sequences did not originate from breast milk or formula, suggesting a non-dietary initial source of viruses. Certain sequences were stable in the infant's gut over the first 3 months of life, but microarray experiments demonstrated that the overall viral community composition changed dramatically between 1 and 2 weeks of age.

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Citation / Publisher Attribution

Research in Microbiology, v. 159, issue 5, p. 367-373