Marine Science Faculty Publications

Viral Diversity and Dynamics in an Infant Gut

Document Type

Article

Publication Date

2008

Keywords

Infant, Feces, Virus, Phage, Metagenomics, Microarray, Gut

Digital Object Identifier (DOI)

https://doi.org/10.1016/j.resmic.2008.04.006

Abstract

Metagenomic sequencing of DNA viruses from the feces of a healthy week-old infant revealed a viral community with extremely low diversity. The identifiable sequences were dominated by phages, which likely influence the diversity and abundance of co-occurring microbes. The most abundant fecal viral sequences did not originate from breast milk or formula, suggesting a non-dietary initial source of viruses. Certain sequences were stable in the infant's gut over the first 3 months of life, but microarray experiments demonstrated that the overall viral community composition changed dramatically between 1 and 2 weeks of age.

Was this content written or created while at USF?

Yes

Citation / Publisher Attribution

Research in Microbiology, v. 159, issue 5, p. 367-373

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