Graduation Year


Document Type




Degree Name

Master of Science (M.S.)

Degree Granting Department


Major Professor

Xiaodong Michael Shi, Ph.D.

Committee Member

James Leahy, Ph.D.

Committee Member

Jianfeng Cai, Ph.D.

Committee Member

Libin Ye, Ph.D.


Ligand, Methodology, VT-NMR, Metal Organic


This thesis contains three parts: 1) The briefly review of chiral P, N-ligands. 2) The summary of triazole as ligands. 3) The attempt of designing, synthesizing the chiral triazole ligands.

In the first part, we have reviewed all the major P, N-ligands in the history, including how they were synthesized and resolved into single enantiomer. We also used some examples to show their utility potential in different reactions.

In the second part, we summarized the triazole ligands which mainly developed by our group including their structures, their potential and utility in different types of chemical reactions.

In the last part, we tried to design, synthesize our own version of chiral triazole ligand. We explored different ways of synthesizing the triazole compound and replacing different substituted groups but it ended up without stable chirality in the room temperature. The goal needs further exploring.