Quantifying non-primary DNA formations through mechanical and geometric models

Authors

Sonia E. Teodorescu, Strawberry Crest High School, Dover, FloridaFollow

Publication Year

2024

Abstract

In this article, mechanical and geometric models for DNA strains (regarded as a helical structure in 3 dimensions, embedded into surfaces of various shapes (straight or curved cylinders, spheres, or projected into planes), are analyzed in order to obtain parameter estimates for DNA characteristics which can be used to detect the formation of secondary and tertiary formations in the presence of disorder. The models allow for the explicit representation of the DNA shape on constrained geometries and can therefore be implemented directly into {\it{ab initio}} or synthetic simulation studies.

Recommended Citation

Teodorescu, Sonia E. (2024) "Quantifying non-primary DNA formations through mechanical and geometric models," Undergraduate Journal of Mathematical Modeling: One + Two: Vol. 13: Iss. 1, Article 2.

Available at: https://digitalcommons.usf.edu/ujmm/vol13/iss1/2

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