Document Type

Patent

Publication Date

4-25-2017

Patent Number

9632076

CPC

G01N 33/5058 (20130101)

Abstract

This application provides devices for modeling ischemic stroke conditions. The devices can be used to culture neurons and to subject a first population of the neurons to low-oxygen conditions and a second population of neurons to normoxic conditions. The neurons are cultured on a porous barrier, and on the other side of the barrier run one or more fluid-filled channels. By flowing fluid with different oxygen levels through the channels, one can deliver desired oxygen concentrations to the cells nearest those channels.

Application Number

14/539,544

Assignees

University of South Florida

Filing Date

2014-11-12

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