Document Type
Patent
Publication Date
3-22-2016
Patent Number
9289421
CPC
A61K 31/416 (20130101)
Abstract
The present disclosure provides methods and pharmaceutical compositions for reducing the serum level of immunoglobulin IgE in an animal or human subject. It has been found that reducing or inhibiting the activity of the cannabinoid receptor CB2 leads to an increase in IgE in serum levels. Conversely, activation of the CB2 receptor by an agonist results in a reduction in IgE serum levels. The compositions and methods of the disclosure, therefore, provide a means to reduce or eliminate symptoms of immune system-related conditions resulting from IgE generation, such as an allergy, hay fever, and the like.
Application Number
14/241,388
Recommended Citation
Klein, Thomas W.; Newton, Catherine; Patterson, Cahterine; and Agudelo, Marisela, "Methods and compositions for reducing serum levels of immunoglobulin E (IgE)" (2016). USF Patents. 842.
https://digitalcommons.usf.edu/usf_patents/842
Assignees
University of South Florida
Filing Date
2012-08-29
