Document Type

Patent

Publication Date

February 2006

Patent Number

7002003

Abstract

There is provided a method of modulating the function of transcription factor by administering an effective amount of an oligonucleotide containing optimal nucleotide binding sites for the transcription factor. A therapeutic agent having an effective amount of an oligonucleotide for modulating function of transcription factors and a pharmaceutically acceptable carrier is also provided. Also provided is a treatment of patients having illnesses in which the activation of transcription factors play a role by administering to a patient an effective amount of an oligonucleotide which competitively binds the related transcription factor.

Application Number

09/744,875

Assignees

University of South Florida

Filing Date

07/30/1999

Primary/U.S. Class

536/241

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