Document Type
Patent
Publication Date
August 2011
Patent Number
8008273
Abstract
The invention concerns a method for increasing megakaryocyte and megakaryocyte progenitor numbers in vitro or in vivo by suppressing SH2-containing inositol-5-phosphatase (SHIP) function in megakaryocytes or megakaryocyte progenitors expressing the SHIP gene. SHIP function can be suppressed by administering an interfering RNA, or other SHIP inhibitor, to the megakaryocytes or megakaryocyte progenitors in vitro or in vivo.
Application Number
12/819,711
Recommended Citation
Kerr, William G.; Desponts, Caroline; and Perez, Lia Elena, "SHIP-deficiency to increase megakaryocyte progenitor production" (2011). USF Patents. 426.
https://digitalcommons.usf.edu/usf_patents/426
Assignees
University of South Florida
Filing Date
06/21/2010
Primary/U.S. Class
514/44
COinS
