A method of preparing a sol-gel monolithic column includes the step of forming a separation bed (14) from a sol-gel solution in a single process step. This column has improved characteristics for CEC based on its incorporated surface charge and ease of operation due to a lack of or need for end frits. Also, a second type of column includes an optical window (30) for on-column detection.
Malik, Abdul and Hayes, James D., "Sol-gel monolithic column with optical window and method of making" (2011). USF Patents. 399.
University of South Florida