Document Type
Patent
Publication Date
December 2012
Patent Number
8337829
Abstract
The subject invention pertains to tumor cell lines useful for increasing the proliferation potential of any human or animal cell in culture, thereby providing immortalized or continuous cell lines and cultures. The invention also concerns proliferation factors, and compositions containing the factors, which are capable of increasing the proliferation potential of any human or other animal cell in culture. The subject invention further pertains to a method for proliferating cells in culture by contacting cells with the proliferation factors. The proliferated cells can range in plasticity and can include, for example, blast cells, fertilized ova, non-fertilized gametes, embryonic stem cells, adult stem cells, precursor or progenitor cells, and highly specialized cells. Optionally, the cells can be induced to cease proliferation. The proliferated cells of the subject invention are useful for cell therapy, cell/gene therapy, biological production of molecules, and as in vitro models for research, toxicity testing, and drug development.
Application Number
13/267,346
Recommended Citation
Freeman, Thomas B.; Caviedes, Pablo; and Caviedes, Raul, "Conditioned medium and proliferated cell lines produced therefrom" (2012). USF Patents. 368.
https://digitalcommons.usf.edu/usf_patents/368
Assignees
University of South Florida
Filing Date
10/06/2011
Primary/U.S. Class
424/931