The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers.
Dou, Q. Ping; Chan, Tak-Hang; and Smith, David M., "Polyphenol proteasome inhibitors, synthesis, and methods of use" (2013). USF Patents. 251.
University of South Florida McGill University The Hong Kong Polytechnic University