Document Type
Patent
Publication Date
June 2013
Patent Number
8455228
Abstract
A method for facilitating a delivery of a molecule into an interior space of a cell includes the steps of introducing a molecule into a biological structure comprising a cell and applying a substantially continuous low-level electric field, in the form of non-thermal plasma (ionized gas) generated by a direct current voltage applied to an electrode, to the molecule and biological structure. The field is applied for a duration sufficient to effect a change in porosity the cell of the biological structure sufficient to facilitate an entry of a desired molecule into an interior thereof.
Application Number
12/207,846
Recommended Citation
Jaroszeski, Mark; Lopez-Diaz, Gabriel A.; Connolly, Richard J.; and Hoff, Andrew M., "Method to facilitate directed delivery and electroporation using a charged stream" (2013). USF Patents. 220.
https://digitalcommons.usf.edu/usf_patents/220
Assignees
University of South Florida
Filing Date
09/10/2008
Primary/U.S. Class
435/173
