Document Type

Patent

Publication Date

March 2013

Patent Number

8404671

Abstract

The invention relates to heterosubstituted N-thiolated beta-lactams, compositions comprising these compounds, methods for their production, and methods of use as antibiotics to inhibit the growth of bacteria. In one embodiment, the compounds have the structure shown in formula (A) or formula (B) or formula (C):

wherein the R groups are as defined in the specification. The antibacterial agents of the invention can be administered to a human or animal to treat or inhibit bacterial infection, such as that of Staphylococcus species, including methicillin-resistant Staphylococcus aureus (MRSA).

Application Number

12/951,778

Assignees

University of South Florida

Filing Date

11/22/2010

Primary/U.S. Class

514/210

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