Document Type

Patent

Publication Date

October 2014

Patent Number

8853149

CPC

C07K 7/06(20130101), A61K 38/00(20130101)

Abstract

Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically effective amount of the integrin interaction inhibitor. Data show that integrin interaction inhibitors act synergistically or additively interact with anti-proliferative agents such as doxorubicin, SAHA, arsenic trioxide, and etoposide.

Application Number

13/636,010

Assignees

H. Lee Moffitt Cancer Center and Research Institute, Inc. University of South Florida

Filing Date

03/21/2011

Primary/U.S. Class

514/11

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