Document Type

Article

Publication Date

June 2025

Patent Number

12331362

CPC

C12Q 1/6886 , C12Q 1/6883 , C12Q 2600/106 , C12N 15/11 , C12N 2310/113 , C12N 2320/30 , C12N 15/113 , A61K 48/005 , A61K 31/7105

Abstract

Provided herein are methods of measuring C19MC miRNA amount and/or expression in a post-natal cell and/or tissue. Provided herein are methods of measuring CpG methylation of the upstream C19MC miRNA promoter region in a post-natal cell and/or tissue. Also provided herein are methods of treating a cell, population thereof, and/or a subject in need thereof by administering a C19MC miRNA inhibitor or CRISPR to suppress the expression of specific miRNA within the C19MC or the entire C19MC cluster, population thereof, and/or the subject in need thereof.

Application Number

17/509648

Assignees

UNIVERSITY OF SOUTH FLORIDA

Filing Date

10/25/2021

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