Document Type

Article

Publication Date

January 2025

Patent Number

12194026

CPC

A61K 31/4245 , A61P 25/00 , A61P 27/16

Abstract

Compounds, pharmaceutical compositions, and methods for treating tinnitus in a subject in need thereof. The methods include administering a therapeutically effective amount of a compound having a structure represented by Formula I as described herein. The compounds and compositions are administered transdermally or orally, preferably via a sustained release mechanism. The compounds and compositions reduce at least one behavioral correlate of tinnitus and/or at least one neurophysiological correlate of tinnitus. The compounds and compositions reduce hyperactivity in the auditory system.

Application Number

17/288718

Assignees

UNIVERSITY OF SOUTH FLORIDA

Filing Date

08/26/2019

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