C12N 5/0636, A61K 35/12
Disclosed are compositions and methods for ex vivo expansion of tumor-infiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an agent for ex vivo expansion of tumor-infiltrating lymphocytes for use in ACT. Also disclosed are methods for treating cancer using tumor-infiltrating lymphocytes expanded by the disclosed methods.
Sarnaik, Amod A.; Pilon-Thomas, Shari; McLaughlin, Mark; and Liu, Hao, "Tumor-infiltrating lymphocytes for adoptive cell therapy" (2022). USF Patents. 1315.
H. Lee Moffitt Cancer Center and Research Institute, Inc.