A61K 31/055, A61K 9/0019, A61P 25/28
Disclosed herein are compositions and methods for treating tauopathies such as Alzheimer's disease (AD). Also provided herein are methods of reducing or disrupting tau aggregation in a subject, and methods of reducing tau protein in a subject. The methods may include administering to the subject a therapeutic amount of hexachlorophene, or a pharmaceutically acceptable salt thereof. Further provided herein are pharmaceutical compositions comprising hexachlorophene, or a pharmaceutically acceptable salt thereof, for the treatment of a tauopathy in a subject.
Jinwal, Umesh Kumar and Manavalan, Vetriselvan, "Compositions and methods for the treatment of tauopathies" (2020). USF Patents. 1164.
University of South Florida