C12N 15/111, C12N 2310/14, A61K 31/713, A61K 48/0033
Provided herein are methods of measuring C19MC miRNA amount and/or expression in a post-natal cell and/or tissue. Provided herein are methods of measuring CpG methylation of the upstream C19MC miRNA promoter region in a post-natal cell and/or tissue. Also provided herein are methods of treating a cell, population thereof, and/or a subject in need thereof by administering a C19MC miRNA inhibitor or CRISPR to suppress the expression of specific miRNA within the C19MC or the entire C19MC cluster, population thereof, and/or the subject in need thereof.
Totary-Jain, Hana and Mong, Ezinne Francess, "Methods of measuring C19MC miRNA in a post-natal tissue and uses thereof" (2019). USF Patents. 1031.
University of South Florida