Document Type

Patent

Publication Date

October 2019

Patent Number

10435757

CPC

C12N 15/111, C12N 2310/14, A61K 31/713, A61K 48/0033

Abstract

Provided herein are methods of measuring C19MC miRNA amount and/or expression in a post-natal cell and/or tissue. Provided herein are methods of measuring CpG methylation of the upstream C19MC miRNA promoter region in a post-natal cell and/or tissue. Also provided herein are methods of treating a cell, population thereof, and/or a subject in need thereof by administering a C19MC miRNA inhibitor or CRISPR to suppress the expression of specific miRNA within the C19MC or the entire C19MC cluster, population thereof, and/or the subject in need thereof.

Application Number

15/623832

Assignees

University of South Florida

Filing Date

06/15/2017

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