Big Data Analysis of Drug Induced Hypersensitivity and Anaphylaxis Reactions in Clinical Cancer Trials
Cancer, Clinical trials, Data management, Data processing, Data analysis, Anaphylaxis, Studies, Hypersensitivity
Digital Object Identifier (DOI)
The dataset, which included study name, medical condition, intervention, arm titles, and adverse drug reactions, was queried for drug hypersensitivity reactions using the key terms: hypersensitivity, allergic reaction, allergy, anaphylaxis, allergic dermatitis, and drug hypersensitivity. Results Preliminary population analysis of 425 of the 1605 qualifying clinical trials from this dataset revealed 3,013 adverse drug hypersensitivity reactions of 118,159 patients at risk for HSRs (2.5% incidence).
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Citation / Publisher Attribution
Journal of Allergy and Clinical Immunology, v. 121, issue 2, p. AB87
Scholar Commons Citation
Eldredge, Christina; Singavi, Arun; Lam, Cesar; Gallagher, Joel; and Luo, Jake, "Big Data Analysis of Drug Induced Hypersensitivity and Anaphylaxis Reactions in Clinical Cancer Trials" (2018). School of Information Faculty Publications. 446.