Excitotoxic Lesions of the Gustatory Thalamus Spare Simultaneous Contrast Effects But Eliminate Anticipatory Negative Contrast: Evidence against a Memory Deficit

Document Type


Publication Date



gustatory thalamus, negative contrast, taste stimuli, thalamic lesions, gustatory memory, contrast effects, lesion-induced disruption, simultaneous contrast, anticipatory contrast, memory deficit

Digital Object Identifier (DOI)



Using consummately contrast procedures and the same taste stimuli (0.15% saccharin and 1.0 M sucrose), the authors tested the hypothesis that lesions of the gustatory thalamus disrupt gustatory memory in 2 experiments. In Experiment 1, irrespective of the duration of the intersolution interval (0 s, 30 s, 1 min, 2 min, 4 min, 8 min), thalamic lesions had no influence on the expression of simultaneous contrast effects. In Experiment 2, thalamic lesions abolished anticipatory negative contrast at the 0-s intersolution interval. These results provide no support for the experimental hypothesis. Rather, the data seem best interpreted as a lesion-induced disruption of the comparison mechanism responsible for anticipatory negative contrast. By this analysis, different comparison mechanisms underlie simultaneous and anticipatory contrast effects.

Was this content written or created while at USF?


Citation / Publisher Attribution

Behavioral Neuroscience, v. 118, issue 2, p. 365-376