Document Type

Article

Publication Date

2013

Keywords

Breakpoint, Cancer Genome, Chromothripsis, Genome Rearrangements, Structural Variation

Digital Object Identifier (DOI)

https://doi.org/10.4161/idp.25954

Abstract

In their recent paper, Malhotra et al. performed a comprehensive analysis of the structural variation breakpoints in 64 cancer genomes from 7 tumor types to find the prevalence and origins of complex genomic rearrangements.1 Since this work represents a breakthrough in understanding of the molecular mechanisms underlying complex cancer genome rearrangements, we provide a brief overview of this outstanding study.

Rights Information

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.

Was this content written or created while at USF?

Yes

Citation / Publisher Attribution

Intrinsically Disordered Proteins, v. 1, issue 1, art. e25954

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