Breakpoint, Cancer Genome, Chromothripsis, Genome Rearrangements, Structural Variation
Digital Object Identifier (DOI)
In their recent paper, Malhotra et al. performed a comprehensive analysis of the structural variation breakpoints in 64 cancer genomes from 7 tumor types to find the prevalence and origins of complex genomic rearrangements.1 Since this work represents a breakthrough in understanding of the molecular mechanisms underlying complex cancer genome rearrangements, we provide a brief overview of this outstanding study.
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Citation / Publisher Attribution
Intrinsically Disordered Proteins, v. 1, issue 1, art. e25954
Scholar Commons Citation
Hedlund, Robert and Uversky, Vladimir N., "Understanding The Molecular Mechanisms Underlying Complex Cancer Genome Rearrangements" (2013). Molecular Medicine Faculty Publications. 448.