Title

Circadian rhythms in Mexican blind cavefish Astyanax mexicanus in the lab and in the field

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Publication Date

November 2013

Abstract

Biological clocks have evolved as an adaptation to life on a rhythmic planet, synchronising physiological processes to the environmental light–dark cycle. Here we examine circadian clock function in Mexican blind cavefish Astyanax mexicanus and its surface counterpart. In the lab, adult surface fish show robust circadian rhythms in per1, which are retained in cave populations, but with substantial alterations. These changes may be due to increased levels of light-inducible genes in cavefish, including clock repressor per2. From a molecular standpoint, cavefish appear as if they experience ‘constant light’ rather than perpetual darkness. Micos River samples show similar per1 oscillations to those in the lab. However, data from Chica Cave shows complete repression of clock function, while expression of several light-responsive genes is raised, including DNA repair genes. We propose that altered expression of light-inducible genes provides a selective advantage to cavefish at the expense of a damped circadian oscillator.

Notes

Nature Communications, Vol. 4, no. 2769 (2013-11-14).

Keywords

Mexican, Blind Cavefish, Astyanax Mexicanus

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1 online resource

Subject: topical

Mexican, Blind Cavefish, Astyanax Mexicanus

Type

Article

Genre

Serial publications

Identifier

SFS0050408_00001

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