Title

Bats are natural reservoirs of SARS-like coronaviruses

Creator

Wendong Li
Zhengli Shi
Meng Yu
Wuze Ren
Craig Smith
Jonathan H. Epstein
Hanzhong Wang
Gary Crameri
Zhihong Hu
Huajun Zhang
Jianhong Zhang
Jennifer McEachern
Hume Field
Peter Daszak
Bryan T. Eaton
Shuyi Zhang
Lin-Fa Wang

Files

Publication Date

October 2005

Abstract

Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group.

Keywords

Bats, Coronaviruses, SARS (Disease), Asia, China

Type

Article

Publisher

American Association for the Advancement of Science

Identifier

K26-05404

Recommended Citation

Li, Wendong; Shi, Zhengli; Yu, Meng; Ren, Wuze; Smith, Craig; Epstein, Jonathan H.; Wang, Hanzhong; Crameri, Gary; Hu, Zhihong; Zhang, Huajun; Zhang, Jianhong; McEachern, Jennifer; Field, Hume; Daszak, Peter; Eaton, Bryan T.; Zhang, Shuyi; and Wang, Lin-Fa, "Bats are natural reservoirs of SARS-like coronaviruses" (2005). KIP Articles. 394.
https://digitalcommons.usf.edu/kip_articles/394