Biopsy, cryoprobe, neuroendocrine, transbronchial, DIPNECH
Digital Object Identifier (DOI)
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) remains a poorly understood clinical entity. It is currently classified as a premalignant condition by the World Health Organization (WHO). Symptoms are similar to those associated with obstructive lung disease, including breathlessness and cough. The presentation is often initially ascribed to other diseases such as asthma or chronic obstructive pulmonary disease. Here, we present what we believe is the first described case of DIPNECH diagnosed by transbronchoscopic cryoprobe biopsy. The patient presented with chronic cough, dyspnoea, pulmonary function tests consistent with obstruction, and a computed tomography (CT) scan of chest with multiple nodules. The patient went on to have transbronchoscopic cryoprobe biopsies of the lung, which confirmed the diagnosis of DIPNECH.
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Was this content written or created while at USF?
Citation / Publisher Attribution
Respirology Case Reports, v. 5, issue 6, art. e0275
Scholar Commons Citation
Patel, Ravi; Collazo-Gonzalez, Carolina; Andrews, Arthur; Rumbak, Mark; and Smith, Maxwell, "Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia Diagnosed by Tranbronchoscopic Cryoprobe Biopsy Technique" (2017). Internal Medicine Faculty Publications. 119.