Graduation Year

2024

Document Type

Dissertation

Degree

Ph.D.

Degree Name

Doctor of Philosophy (Ph.D.)

Degree Granting Department

Nursing

Major Professor

Theresa M. Beckie, Ph.D.

Committee Member

Ponrathi Athilingam, Ph.D.

Committee Member

Ayesha Johnson, Ph.D.

Committee Member

Andrew Bugajski, Ph.D.

Committee Member

Christopher Lee, Ph.D.

Committee Member

Arch Amon, M.D.

Keywords

comorbidity, quality of life, self-care, symptoms

Abstract

As the prevalence of many chronic cardiopulmonary illnesses are expected to rise within the United States through 2030, there is a growing emphasis on investigating the patient-reported outcomes relevant to the morbidity and social burden of these diseases. Thus, the overall aim of this dissertation is to examine these outcomes among those that live with chronic obstructive pulmonary disease and cardiovascular diseases (namely, heart failure). Specifically, the works in this dissertation aimed to compare how individuals report their health-related quality of life when living with and without cardiovascular disease across the spectrum of airflow limitation demonstrated within chronic obstructive pulmonary disease, to identify symptom trajectories over time among those living with either or both chronic obstructive pulmonary disease, and to assess whether there may be significant associations with self-care and experiencing one of the identified symptom trajectories in the aforementioned population, elucidated through advanced quantitative inquiry such as factorial analysis of variance and growth mixture modeling. Variable perceptions of health-related quality of life, symptom experiences, and self-care behaviors are demonstrated throughout this body of work. This dissertation adds to the existing body of literature given its advanced approaches to inquiry and consideration of the impacts of comorbidity on these outcomes.

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