Factors Associated with High Hospital Resource Use in a Population-based Study of Children with Orofacial Clefts
orofacial clefts, health services research, resource use, hospitalization, cost, cleft lip, cleft palate
Digital Object Identifier (DOI)
Background: Little is known about population-based maternal, child, and system characteristics associated with high hospital resource use for children with orofacial clefts (OFC) in the US.
Methods: This was a statewide, population-based, retrospective observational study of children with OFC born between 1998 and 2006, identified by the Florida Birth Defects Registry whose records were linked with longitudinal hospital discharge records. We stratified the descriptive results by cleft type [cleft lip with cleft palate, cleft lip, and cleft palate] and by isolated versus nonisolated OFC (accompanied by other coded major birth defects). We used Poisson regression to analyze associations between selected characteristics and high hospital resource use (≥90th percentile of estimated hospitalized days and inpatient costs) for birth, postbirth, and total hospitalizations initiated before age 2 years.
Results: Our analysis included 2,129 children with OFC. Infants who were born low birth weight (<2500 >grams) were significantly more likely to have high birth hospitalization costs for CLP (adjusted prevalence ratio: 1.6 [95% confidence interval: 1.0–2.7]), CL (adjusted prevalence ratio: 3.0 [95% confidence interval: 1.1–8.1]), and CP (adjusted prevalence ratio: 2.3 [95% confidence interval: 1.3–4.0]). Presence of multiple birth defects was significantly associated with a three- to eleven-fold and a three- to nine-fold increase in the prevalence of high costs and number of hospitalized days, respectively; at birth, postbirth before age 2 years
Conclusion: Children with cleft palate had the greatest hospital resources use. Additionally, the presence of multiple birth defects contributed to greater inpatient days and costs for children with OFC. Birth Defects Research (Part A) 103:127–143, 2015 © 2015 Wiley Periodicals, Inc.
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Citation / Publisher Attribution
Birth Defects Research Part A: Clinical and Molecular Teratology, v. 103, issue 2, p. 127-143
Scholar Commons Citation
Razzaghi, Hilda; Dawson, April; Grosse, Scott D.; Allori, Alexander C.; Kirby, Russell S.; Olney, Richard S.; Correia, Jane; and Cassell, Cynthia H., "Factors Associated with High Hospital Resource Use in a Population-based Study of Children with Orofacial Clefts" (2015). Community and Family Health Faculty Publications. 64.